Browse
Submit Data
Databases
API
Help

Dataset Information

26 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Coronavirus disease 2019 in pregnant and non-pregnant women: a retrospective study.

ABSTRACT:

SUBMITTER: Zha Y

PROVIDER: S-EPMC8143774 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Endometrial gene expression differences in women with coronavirus disease 2019

Project description:Objective: To study the potential effect of COVID-19 on the endometrium of affected symptomatic women. Design: Preliminary study of the endometrial transcriptomes in women with COVID-19 through RNA sequencing. Setting: Hospital and university laboratories. Subjects: Women with COVID-19 lacking SARS-CoV-2 infection in endometrial tissue. Intervention/Exposure: Endometrial biopsy collection. Main outcomes measures: Endometrial gene expression and functional analysis of patients with COVID-19 versus uninfected individuals. Results: COVID-19 systemic disease alters endometrial gene expression in 75% of women, with patients exhibiting a preponderance of 163 up-regulated (e.g., UTS2, IFI6, IFIH1, BNIP3) and 72 down-regulated genes (e.g., CPZ, CDH3, IRF4) (FDR<0.05). A total of 161 dysregulated functions (36 up-regulated and 125 down-regulated) were typically enriched in COVID-19 endometria, including upregulation in pathways involved in response to virus and cytokine inflammation, highlighting upregulation of a COVID-19 response pathway. Conclusion: COVID-19 affects endometrial gene expression despite the absence of SARS-CoV-2 particles in endometrial tissues.

2024-04-22 | GSE202553 | GEO

Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study.

Project description: Not available

| S-EPMC7997025 | biostudies-literature

Clinical features and outcomes of pregnant women suspected of coronavirus disease 2019.

Project description: Not available

| S-EPMC7152867 | biostudies-literature

Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019.

Project description: Not available

| S-EPMC7797739 | biostudies-literature

Coronavirus disease 2019 in pregnant women: a report based on 116 cases.

Project description: Not available