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Prevalence and risk factors of psychiatric symptoms and diagnoses before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 mental health cohort.


ABSTRACT:

Background

There is mixed evidence on increasing rates of psychiatric disorders and symptoms during the coronavirus disease 2019 (COVID-19) pandemic in 2020. We evaluated pandemic-related psychopathology and psychiatry diagnoses and their determinants in the Brazilian Longitudinal Study of Health (ELSA-Brasil) São Paulo Research Center.

Methods

Between pre-pandemic ELSA-Brasil assessments in 2008-2010 (wave-1), 2012-2014 (wave-2), 2016-2018 (wave-3) and three pandemic assessments in 2020 (COVID-19 waves in May-July, July-September, and October-December), rates of common psychiatric symptoms, and depressive, anxiety, and common mental disorders (CMDs) were compared using the Clinical Interview Scheduled-Revised (CIS-R) and the Depression Anxiety Stress Scale-21 (DASS-21). Multivariable generalized linear models, adjusted by age, gender, educational level, and ethnicity identified variables associated with an elevated risk for mental disorders.

Results

In 2117 participants (mean age 62.3 years, 58.2% females), rates of CMDs and depressive disorders did not significantly change over time, oscillating from 23.5% to 21.1%, and 3.3% to 2.8%, respectively; whereas rate of anxiety disorders significantly decreased (2008-2010: 13.8%; 2016-2018: 9.8%; 2020: 8%). There was a decrease along three wave-COVID assessments for depression [β = -0.37, 99.5% confidence interval (CI) -0.50 to -0.23], anxiety (β = -0.37, 99.5% CI -0.48 to -0.26), and stress (β = -0.48, 99.5% CI -0.64 to -0.33) symptoms (all ps < 0.001). Younger age, female sex, lower educational level, non-white ethnicity, and previous psychiatric disorders were associated with increased odds for psychiatric disorders, whereas self-evaluated good health and good quality of relationships with decreased risk.

Conclusion

No consistent evidence of pandemic-related worsening psychopathology in our cohort was found. Indeed, psychiatric symptoms slightly decreased along 2020. Risk factors representing socioeconomic disadvantages were associated with increased odds of psychiatric disorders.

SUBMITTER: Brunoni AR 

PROVIDER: S-EPMC8144814 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Prevalence and risk factors of psychiatric symptoms and diagnoses before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 mental health cohort.

Brunoni André Russowsky AR   Suen Paulo Jeng Chian PJC   Bacchi Pedro Starzynski PS   Razza Lais Boralli LB   Klein Izio I   Dos Santos Leonardo Afonso LA   de Souza Santos Itamar I   da Costa Lane Valiengo Leandro L   Gallucci-Neto José J   Moreno Marina Lopes ML   Pinto Bianca Silva BS   de Cássia Silva Félix Larissa L   de Sousa Juliana Pereira JP   Viana Maria Carmen MC   Forte Pamela Marques PM   de Altisent Oliveira Cardoso Marcia Cristina MC   Bittencourt Marcio Sommer MS   Pelosof Rebeca R   de Siqueira Luciana Lima LL   Fatori Daniel D   Bellini Helena H   Bueno Priscila Vilela Silveira PVS   Passos Ives Cavalcante IC   Nunes Maria Angelica MA   Salum Giovanni Abrahão GA   Bauermeister Sarah S   Smoller Jordan W JW   Lotufo Paulo Andrade PA   Benseñor Isabela Martins IM  

Psychological medicine 20210421 2


<h4>Background</h4>There is mixed evidence on increasing rates of psychiatric disorders and symptoms during the coronavirus disease 2019 (COVID-19) pandemic in 2020. We evaluated pandemic-related psychopathology and psychiatry diagnoses and their determinants in the Brazilian Longitudinal Study of Health (ELSA-Brasil) São Paulo Research Center.<h4>Methods</h4>Between pre-pandemic ELSA-Brasil assessments in 2008-2010 (wave-1), 2012-2014 (wave-2), 2016-2018 (wave-3) and three pandemic assessments  ...[more]

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