Dataset Information

Adsorption and release on three-dimensional graphene oxide network structures.

ABSTRACT: In this study, three-dimensional network architectures are constructed using nano-sized graphene oxide (nGO) as the building block. The cross-linking reaction of nGO is conducted in sub-micrometre water droplets in an emulsion system to control the size of the networks by restricting the reaction space. Two types of three-dimensional GO networks with different cross-linking lengths were constructed, and their methyl orange adsorption and release behaviours were investigated under external stimuli, such as thermal treatment, ultrasonic wave treatment and near-infrared light irradiation.

SUBMITTER: Kim S

PROVIDER: S-EPMC8150017 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Adsorption and release on three-dimensional graphene oxide network structures.

Kim Sunnam S Moriya Sho S Maruki Sakura S Fukaminato Tuyoshi T Ogata Tomonari T Kurihara Seiji S

Royal Society open science 20210526 5

In this study, three-dimensional network architectures are constructed using nano-sized graphene oxide (nGO) as the building block. The cross-linking reaction of nGO is conducted in sub-micrometre water droplets in an emulsion system to control the size of the networks by restricting the reaction space. Two types of three-dimensional GO networks with different cross-linking lengths were constructed, and their methyl orange adsorption and release behaviours were investigated under external stimul ...[more]

PMID: 34084539

Similar Datasets

Project description:The present study focused on investigation of graphene oxide/hydroxyapatite (GO/HAp) and amine modified graphene oxide/hydroxyapatite (GO-NH2/HAp) composites as potential drug carrier agents for 5-Fluorouracil (5-FU). Incorporation of 5-Fluorouracil drug was performed via adsorption through π-π interactions and electrostatic attractions. Modification of graphene oxide was performed for the production of amine modified graphene oxide/hydroxyapatite composite with the intention of enhancing adsorption performance. The X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric Analysis (TGA) and zeta potential/particle size analysis were performed for particle characterization while Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) analysis were used to analyze detailed morphological properties. Experimental design studies were followed out in order to determine the effect of adsorption parameters including graphene oxide amount, pH and initial drug concentration on 5-Fluorouracil adsorption behavior. Adsorption isotherms of both composites with unmodified and modified GO were best fitted to Freundlich model with R2 values of 0.9616 and 0.9682 respectively. The maximum adsorption capacities (qm) were calculated as 47.3 mg/g and 18.4 for graphene oxide/hydroxyapatite and amine modified graphene oxide/hydroxyapatite composites respectively at pH 2.0. The highest adsorption percentage was obtained for amine modified graphene oxide/hydroxyapatite composite as 40.87 % at pH 2.0 condition. In vitro release kinetic studies revealed that compliance with Higuchi and Korsmeyer-Peppas kinetic models were observed for graphene oxide/hydroxyapatite, whereas zero order and Korsmeyer-Peppas kinetic models pointed out as the well-fitted model for amine modified graphene oxide/hydroxyapatite composite. The release period of 5-FU drug from all composites were continued up to 8-10 h in physiological conditions (pH 7.4, 37 °C) indicating an achieved controlled release. Based on the overall findings, graphene oxide/hydroxyapatite and amine modified graphene oxide/hydroxyapatite composites could be suggested as a potential drug delivery agent for 5-FU in clinical applications.

Dataset Information

Adsorption and release on three-dimensional graphene oxide network structures.

Publications

Adsorption and release on three-dimensional graphene oxide network structures.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets