Ontology highlight
ABSTRACT:
SUBMITTER: Deng H
PROVIDER: S-EPMC8151812 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Deng Hai H Tang Ting-Xuan TX Chen Deng D Tang Liang-Sheng LS Yang Xiang-Ping XP Tang Zhao-Hui ZH
Pathogens (Basel, Switzerland) 20210511 5
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), has been recently considered a systemic disorder leading to the procoagulant state. Preliminary studies have shown that SARS-CoV-2 can infect endothelial cells, and extensive evidence of inflammation and endothelial dysfunction has been found in advanced COVID-19. Endothelial cells play a critical role in many physiological processes, such as controlling blood fluidity, leukocyte activati ...[more]