Neural and Behavioral Evidence for Frequency-Selective Context Effects in Rhythm Processing in Humans.
Ontology highlight
ABSTRACT:
SUBMITTER: Lenc T
PROVIDER: S-EPMC8152888 | biostudies-literature |
REPOSITORIES: biostudies-literature
Similar Datasets
Project description:When listening to musical rhythm, humans can perceive and move to beat-like metrical pulses. Recently, it has been hypothesized that meter perception is related to brain activity responding to the acoustic fluctuation of the rhythmic input, with selective enhancement of the brain response elicited at meter-related frequencies. In the current study, electroencephalography (EEG) was recorded while younger (<35) and older (>60) adults listened to rhythmic patterns presented at two different tempi while intermittently performing a tapping task. Despite significant hearing loss compared to younger adults, older adults showed preserved brain activity to the rhythms. However, age effects were observed in the distribution of amplitude across frequencies. Specifically, in contrast with younger adults, older adults showed relatively larger amplitude at the frequency corresponding to the rate of individual events making up the rhythms as compared to lower meter-related frequencies. This difference is compatible with larger N1-P2 potentials as generally observed in older adults in response to acoustic onsets, irrespective of meter perception. These larger low-level responses to sounds have been linked to processes by which age-related hearing loss would be compensated by cortical sensory mechanisms. Importantly, this low-level effect would be associated here with relatively reduced neural activity at lower frequencies corresponding to higher-level metrical grouping of the acoustic events, as compared to younger adults.
| S-EPMC9475293 | biostudies-literature
Project description:Regularity of acoustic rhythms allows predicting a target embedded within a stream thereby improving detection performance and reaction times in spectral detection tasks. In two experiments we examine whether temporal regularity enhances perceptual sensitivity and reduces reaction times using a temporal shift detection task. Participants detected temporal shifts embedded at different positions within a sequence of quintet-sounds. Narrowband quintets were centered around carrier frequencies of 200 Hz, 1100 Hz, or 3100 Hz and presented at presentation rates between 1-8 Hz. We compared rhythmic sequences to control conditions where periodicity was reduced or absent and tested whether perceptual benefits depend on the presentation rate, the spectral content of the sounds, and task difficulty. We found that (1) the slowest rate (1 Hz) led to the largest behavioral effect on sensitivity. (2) This sensitivity improvement is carrier-dependent, such that the largest improvement is observed for low-frequency (200 Hz) carriers compared to 1100 Hz and 3100 Hz carriers. (3) Moreover, we show that the predictive value of a temporal cue and that of a temporal rhythm similarly affect perceptual sensitivity. That is, both the cue and the rhythm induce confident temporal expectancies in contrast to an aperiodic rhythm, and thereby allow to effectively prepare and allocate attentional resources in time. (4) Lastly, periodic stimulation reduces reaction times compared to aperiodic stimulation, both at perceptual threshold as well as above threshold. Similarly, a temporal cue allowed participants to optimally prepare and thereby respond fastest. Overall, our results are consistent with the hypothesis that periodicity leads to optimized predictions and processing of forthcoming input and thus to behavioral benefits. Predictable temporally cued sounds provide a similar perceptual benefit to periodic rhythms, despite an additional uncertainty of target position within periodic sequences. Several neural mechanisms may underlie our findings, including the entrainment of oscillatory activity of neural populations.
| S-EPMC7274376 | biostudies-literature
Project description:Oxytocin (OT) influences other-oriented mental processes (e.g. trust and empathy) and the underlying neural substrates. However, whether and how OT modulates self-oriented processes and the underlying brain activity remains unclear. Using a double-blind, placebo-controlled between-subjects design, we manipulated memory encoding and retrieval of trait adjectives related to the self, a friend and a celebrity in a self-referential task in male adults. Experiment 1 (N?=?51) found that OT vs placebo treatments reduced response times during encoding self-related trait adjectives but increased recognition scores of self-related information during memory retrieval. Experiment 2 (N?=?50) showed similar OT effects on response times during encoding self-related trait adjectives. Moreover, functional magnetic resonance imaging (fMRI) results revealed that OT vs placebo treatments decreased the activity in the medial prefrontal cortex (MPFC) involved in encoding of self-related trait adjectives and weakened the coupling between the MPFC activity and a cultural trait (i.e. interdependence). Experiment 3 (N?=?52) revealed that OT vs placebo treatments increased the right superior frontal activity during memory retrieval of self-related information. The results provide behavioral and fMRI evidence for OT effects on self-referential processing and suggest distinct patterns of OT modulations of brain activities engaged in encoding and retrieval of self-related information.
| S-EPMC5716198 | biostudies-literature
Project description:BackgroundAccidental injury and homicide, relatively common among adolescents, often follow risky behaviors; those are done more by boys and by adolescents with greater behavioral disinhibition (BD).HypothesisNeural processing during adolescents' risky decision-making will differ in youths with greater BD severity, and in males vs. females, both before cautious behaviors and before risky behaviors.Methodology/principal findings81 adolescents (PATIENTS with substance and conduct problems, and comparison youths (Comparisons)), assessed in a 2 x 2 design (PatientsComparisons x Male:Female) repeatedly decided between doing a cautious behavior that earned 1 cent, or a risky one that either won 5 or lost 10 cents. Odds of winning after risky responses gradually decreased. Functional magnetic resonance imaging captured brain activity during 4-sec deliberation periods preceding responses. Most neural activation appeared in known decision-making structures. PATIENTS, who had more severe BD scores and clinical problems than Comparisons, also had extensive neural hypoactivity. Comparisons' greater activation before cautious responses included frontal pole, medial prefrontal cortex, striatum, and other regions; and before risky responses, insula, temporal, and parietal regions. Males made more risky and fewer cautious responses than females, but before cautious responses males activated numerous regions more than females. Before risky behaviors female-greater activation was more posterior, and male-greater more anterior.Conclusions/significanceNeural processing differences during risky-cautious decision-making may underlie group differences in adolescents' substance-related and antisocial risk-taking. Patients reported harmful real-life decisions and showed extensive neural hypoactivity during risky-or-cautious decision-making. Males made more risky responses than females; apparently biased toward risky decisions, males (compared with females) utilized many more neural resources to make and maintain cautious decisions, indicating an important risk-related brain sexual dimorphism. The results suggest new possibilities for prevention and management of excessive, dangerous adolescent risk-taking.
| S-EPMC4503769 | biostudies-literature
Project description:The construct of imageability refers to the extent to which a word evokes a tangible sensation. Previous research (Westbury et al., 2013) suggests that the behavioral effects attributed to a word's imageability can be largely or wholly explained by two objective constructs, contextual density and estimated affect. Here, we extend these previous findings in two ways. First, we show that closely matched stimuli on the three measures of contextual density, estimated affect, and human-judged imageability show a three-way interaction in explaining variance in LD RTs, but that imagebility accounts for no additional variance after contextual density and estimated affect are entered first. Secondly, we demonstrate that the loci and functional connectivity (via graphical models) of the brain regions implicated in processing the three variables during that task are largely over-lapping and similar. These two lines of evidence support the conclusion that the effect usually attributed to human-judged imageability is largely or entirely due to the effects of other correlated measures that are directly computable.
| S-EPMC4945641 | biostudies-literature
Project description:Cannabinoid (CB) receptors are widespread in the nervous system and influence a variety of behaviors. Weakly electric fish have been a useful model system in the study of the neural basis of behavior, but we know nothing of the role played by the CB system. Here, we determine the overall behavioral effect of a nonselective CB receptor agonist, namely Δ9-tetrahydrocannabinol (THC), in the weakly electric fish Apte-ronotus leptorhynchus. Using various behavioral paradigms involving social stimuli, we show that THC decreases locomotor behavior, as in many species, and influences communication and social behavior. Across the different experiments, we found that the propensity to emit communication signals (chirps) and seek social interactions was affected in a context-dependent manner. We explicitly tested this hypothesis by comparing the behavioral effects of THC injection in fish placed in a novel versus a familiar social and physical environment. THC-injected fish were less likely to chirp than control fish in familiar situations but not in novel ones. The tendency to be in close proximity to other fish was affected only in novel environments, with control fish clustering more than THC-injected ones. By identifying behaviors affected by CB agonists, our study can guide further comparative and neurophysiological studies of the role of the CB system using a weakly electric fish as a model.
| S-EPMC6446089 | biostudies-literature
Project description:Cognitive and behavioral processes are often accompanied by changes within well-defined frequency bands of the local field potential (LFP i.e., the voltage induced by neuronal activity). These changes are detectable in the frequency domain using the Fourier transform and are often interpreted as neuronal oscillations. However, aside some well-known exceptions, the processes underlying such changes are difficult to track in time, making their oscillatory nature hard to verify. In addition, many non-periodic neural processes can also have spectra that emphasize specific frequencies. Thus, the notion that spectral changes reflect oscillations is likely too restrictive. In this study, we propose a simple yet versatile framework to understand the frequency spectra of neural recordings. Using simulations, we derive the Fourier spectra of periodic, quasi-periodic and non-periodic neural processes having diverse waveforms, illustrating how these attributes shape their spectral signatures. We then show how neural processes sum their energy in the local field potential in simulated and real-world recording scenarios. We find that the spectral power of neural processes is essentially determined by two aspects: 1) the distribution of neural events in time and 2) the waveform of the voltage induced by single neural events. Taken together, this work guides the interpretation of the Fourier spectrum of neural recordings and indicates that power increases in specific frequency bands do not necessarily reflect periodic neural activity.
| S-EPMC10197620 | biostudies-literature
Project description:Cognitive and behavioral processes are often accompanied by changes within well-defined frequency bands of the local field potential (LFP i.e., the voltage induced by neuronal activity). These changes are detectable in the frequency domain using the Fourier transform and are often interpreted as neuronal oscillations. However, aside some well-known exceptions, the processes underlying such changes are difficult to track in time, making their oscillatory nature hard to verify. In addition, many non-periodic neural processes can also have spectra that emphasize specific frequencies. Thus, the notion that spectral changes reflect oscillations is likely too restrictive. In this study, we use a simple yet versatile framework to understand the frequency spectra of neural recordings. Using simulations, we derive the Fourier spectra of periodic, quasi-periodic and non-periodic neural processes having diverse waveforms, illustrating how these attributes shape their spectral signatures. We then show how neural processes sum their energy in the local field potential in simulated and real-world recording scenarios. We find that the spectral power of neural processes is essentially determined by two aspects: (1) the distribution of neural events in time and (2) the waveform of the voltage induced by single neural events. Taken together, this work guides the interpretation of the Fourier spectrum of neural recordings and indicates that power increases in specific frequency bands do not necessarily reflect periodic neural activity.
| S-EPMC10500127 | biostudies-literature
Project description:Although Schizophrenia (SCZ) and Autism Spectrum Disorder (ASD) share impairments in emotion recognition, the mechanisms underlying these impairments may differ. The current study used the novel "Emotions in Context" task to examine how the interpretation and visual inspection of facial affect is modulated by congruent and incongruent emotional contexts in SCZ and ASD. Both adults with SCZ (n= 44) and those with ASD (n= 21) exhibited reduced affect recognition relative to typically-developing (TD) controls (n= 39) when faces were integrated within broader emotional scenes but not when they were presented in isolation, underscoring the importance of using stimuli that better approximate real-world contexts. Additionally, viewing faces within congruent emotional scenes improved accuracy and visual attention to the face for controls more so than the clinical groups, suggesting that individuals with SCZ and ASD may not benefit from the presence of complementary emotional information as readily as controls. Despite these similarities, important distinctions between SCZ and ASD were found. In every condition, IQ was related to emotion-recognition accuracy for the SCZ group but not for the ASD or TD groups. Further, only the ASD group failed to increase their visual attention to faces in incongruent emotional scenes, suggesting a lower reliance on facial information within ambiguous emotional contexts relative to congruent ones. Collectively, these findings highlight both shared and distinct social cognitive processes in SCZ and ASD that may contribute to their characteristic social disabilities.
| S-EPMC4838097 | biostudies-literature
Project description:In spite of the reduced visual acuity, parafoveal information plays an important role in natural reading. However, competing models on reading disagree on whether words are previewed parafoveally at the lexical level. We find neural evidence for lexical parafoveal processing by combining a rapid invisible frequency tagging (RIFT) approach with magnetoencephalography (MEG) and eye-tracking. In a silent reading task, target words are tagged (flickered) subliminally at 60 Hz. The tagging responses measured when fixating on the pre-target word reflect parafoveal processing of the target word. We observe stronger tagging responses during pre-target fixations when followed by low compared with high lexical frequency targets. Moreover, this lexical parafoveal processing is associated with individual reading speed. Our findings suggest that reading unfolds in the fovea and parafovea simultaneously to support fluent reading.
| S-EPMC8413448 | biostudies-literature