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Proposal for Human Respiratory Syncytial Virus Nomenclature below the Species Level.


ABSTRACT: Human respiratory syncytial virus (HRSV) is the leading viral cause of serious pediatric respiratory disease, and lifelong reinfections are common. Its 2 major subgroups, A and B, exhibit some antigenic variability, enabling HRSV to circulate annually. Globally, research has increased the number of HRSV genomic sequences available. To ensure accurate molecular epidemiology analyses, we propose a uniform nomenclature for HRSV-positive samples and isolates, and HRSV sequences, namely: HRSV/subgroup identifier/geographic identifier/unique sequence identifier/year of sampling. We also propose a template for submitting associated metadata. Universal nomenclature would help researchers retrieve and analyze sequence data to better understand the evolution of this virus.

SUBMITTER: Salimi V 

PROVIDER: S-EPMC8153853 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Proposal for Human Respiratory Syncytial Virus Nomenclature below the Species Level.

Salimi Vahid V   Viegas Mariana M   Trento Alfonsina A   Agoti Charles N CN   Anderson Larry J LJ   Avadhanula Vasanthi V   Bahl Justin J   Bont Louis L   Brister J Rodney JR   Cane Patricia A PA   Galiano Mónica M   Graham Barney S BS   Hatcher Eneida L EL   Hellferscee Orienka O   Henke David M DM   Hirve Siddhivinayak S   Jackson Sandra S   Keyaerts Els E   Kragten-Tabatabaie Leyla L   Lindstrom Stephen S   Nauwelaers Inne I   Nokes D James DJ   Openshaw Peter J PJ   Peret Teresa C TC   Piedra Pedro A PA   Ramaekers Kaat K   Rector Annabel A   Trovão Nídia Sequeira NS   von Gottberg Anne A   Zambon Maria M   Zhang Wenqing W   Williams Thomas C TC   Barr Ian G IG   Buchholz Ursula J UJ  

Emerging infectious diseases 20210601 6


Human respiratory syncytial virus (HRSV) is the leading viral cause of serious pediatric respiratory disease, and lifelong reinfections are common. Its 2 major subgroups, A and B, exhibit some antigenic variability, enabling HRSV to circulate annually. Globally, research has increased the number of HRSV genomic sequences available. To ensure accurate molecular epidemiology analyses, we propose a uniform nomenclature for HRSV-positive samples and isolates, and HRSV sequences, namely: HRSV/subgrou  ...[more]

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