Transformation of antiviral ribavirin during ozone/PMS intensified disinfection amid COVID-19 pandemic.

ABSTRACT: Due to the spread of coronavirus disease 2019 (COVID-19), large amounts of antivirals were consumed and released into wastewater, posing risks to the ecosystem and human health. Ozonation is commonly utilized as pre-oxidation process to enhance the disinfection of hospital wastewater during COVID-19 spread. In this study, the transformation of ribavirin, antiviral for COVID-19, during ozone/PMS‑chlorine intensified disinfection process was investigated. •OH followed by O₃ accounted for the dominant ribavirin degradation in most conditions due to higher reaction rate constant between ribavirin and •OH vs. SO₄•^- (1.9 × 10⁹ vs. 7.9 × 10⁷ M^-1 s^-1, respectively). During the O₃/PMS process, ribavirin was dehy

SUBMITTER: Liu X 

PROVIDER: S-EPMC8154182 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature