Ontology highlight
ABSTRACT:
SUBMITTER: Krawczyk MS
PROVIDER: S-EPMC8156396 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Krawczyk Marta S MS Sroka Adam A Majerz Irena I
Molecules (Basel, Switzerland) 20210516 10
In order to improve pharmaceutical properties of drugs, complexes are synthesized as combinations with other chemical substances. The complexes of fenamic acid and its derivatives, such as mefenamic-, tolfenamic- and flufenamic acid, with acridine were obtained and the X-ray structures were discussed. Formation of the crystals is determined by the presence of the intermolecular O-H<sup>…</sup>N hydrogen bond that occur between fenamic acids and acridine. Intermolecular interactions stabilizing t ...[more]