Clinical Character of CASPR2 Autoimmune Encephalitis: A Multiple Center Retrospective Study.

ABSTRACT:

Objective

To examine the clinical characteristics of autoimmune encephalitis associated with the contactin-associated protein-2 (CASPR2) antibody.

Materials and methods

Medical records of all patients diagnosed with CASPR2 antibody-associated encephalitis were retrospectively analysed. Data regarding demographic features, neurological symptoms and signs, laboratory tests, imaging results, treatments, and prognosis were collected.

Results

A total of 25 patients aged from 3 to 79 years old were enrolled in this study, with a median age of 43. Eight of 25 (32%) were female, and 17 of 25 (68%) were male. The median age of symptom onset was 42 years old with the course of disease from onset to hospital admission ranging from 2 days to 6 months (median was 17 days). Six pat

SUBMITTER: Qin X 

PROVIDER: S-EPMC8159154 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature