Skin Cancer Detection: A Review Using Deep Learning Techniques.
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ABSTRACT:
SUBMITTER: Dildar M
PROVIDER: S-EPMC8160886 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:Skin lesions are essential for the early detection and management of a number of dermatological disorders. Learning-based methods for skin lesion analysis have drawn much attention lately because of improvements in computer vision and machine learning techniques. A review of the most-recent methods for skin lesion classification, segmentation, and detection is presented in this survey paper. The significance of skin lesion analysis in healthcare and the difficulties of physical inspection are discussed in this survey paper. The review of state-of-the-art papers targeting skin lesion classification is then covered in depth with the goal of correctly identifying the type of skin lesion from dermoscopic, macroscopic, and other lesion image formats. The contribution and limitations of various techniques used in the selected study papers, including deep learning architectures and conventional machine learning methods, are examined. The survey then looks into study papers focused on skin lesion segmentation and detection techniques that aimed to identify the precise borders of skin lesions and classify them accordingly. These techniques make it easier to conduct subsequent analyses and allow for precise measurements and quantitative evaluations. The survey paper discusses well-known segmentation algorithms, including deep-learning-based, graph-based, and region-based ones. The difficulties, datasets, and evaluation metrics particular to skin lesion segmentation are also discussed. Throughout the survey, notable datasets, benchmark challenges, and evaluation metrics relevant to skin lesion analysis are highlighted, providing a comprehensive overview of the field. The paper concludes with a summary of the major trends, challenges, and potential future directions in skin lesion classification, segmentation, and detection, aiming to inspire further advancements in this critical domain of dermatological research.
| S-EPMC10572538 | biostudies-literature
Project description:An increasing number of genetic and metabolic anomalies have been determined to lead to cancer, generally fatal. Cancerous cells may spread to any body part, where they can be life-threatening. Skin cancer is one of the most common types of cancer, and its frequency is increasing worldwide. The main subtypes of skin cancer are squamous and basal cell carcinomas, and melanoma, which is clinically aggressive and responsible for most deaths. Therefore, skin cancer screening is necessary. One of the best methods to accurately and swiftly identify skin cancer is using deep learning (DL). In this research, the deep learning method convolution neural network (CNN) was used to detect the two primary types of tumors, malignant and benign, using the ISIC2018 dataset. This dataset comprises 3533 skin lesions, including benign, malignant, nonmelanocytic, and melanocytic tumors. Using ESRGAN, the photos were first retouched and improved. The photos were augmented, normalized, and resized during the preprocessing step. Skin lesion photos could be classified using a CNN method based on an aggregate of results obtained after many repetitions. Then, multiple transfer learning models, such as Resnet50, InceptionV3, and Inception Resnet, were used for fine-tuning. In addition to experimenting with several models (the designed CNN, Resnet50, InceptionV3, and Inception Resnet), this study's innovation and contribution are the use of ESRGAN as a preprocessing step. Our designed model showed results comparable to the pretrained model. Simulations using the ISIC 2018 skin lesion dataset showed that the suggested strategy was successful. An 83.2% accuracy rate was achieved by the CNN, in comparison to the Resnet50 (83.7%), InceptionV3 (85.8%), and Inception Resnet (84%) models.
| S-EPMC9324455 | biostudies-literature
Project description:BackgroundThe conventional procedure of skin-related disease detection is a visual inspection by a dermatologist or a primary care clinician, using a dermatoscope. The suspected patients with early signs of skin cancer are referred for biopsy and histopathological examination to ensure the correct diagnosis and the best treatment. Recent advancements in deep convolutional neural networks (CNNs) have achieved excellent performance in automated skin cancer classification with accuracy similar to that of dermatologists. However, such improvements are yet to bring about a clinically trusted and popular system for skin cancer detection.ObjectiveThis study aimed to propose viable deep learning (DL) based method for the detection of skin cancer in lesion images, to help physicians in diagnosis.Material and methodsIn this analytical study, a novel DL based model was proposed, in which other than the lesion image, the patient's data, including the anatomical site of the lesion, age, and gender were used as the model input to predict the type of the lesion. An Inception-ResNet-v2 CNN pretrained for object recognition was employed in the proposed model.ResultsBased on the results, the proposed method achieved promising performance for various skin conditions, and also using the patient's metadata in addition to the lesion image for classification improved the classification accuracy by at least 5% in all cases investigated. On a dataset of 57536 dermoscopic images, the proposed approach achieved an accuracy of 89.3%±1.1% in the discrimination of 4 major skin conditions and 94.5%±0.9% in the classification of benign vs. malignant lesions.ConclusionThe promising results highlight the efficacy of the proposed approach and indicate that the inclusion of the patient's metadata with the lesion image can enhance the skin cancer detection performance.
| S-EPMC9759648 | biostudies-literature
Project description:Automatic detection of intact tomatoes on plants is highly expected for low-cost and optimal management in tomato farming. Mature tomato detection has been wildly studied, while immature tomato detection, especially when occluded with leaves, is difficult to perform using traditional image analysis, which is more important for long-term yield prediction. Therefore, tomato detection that can generalize well in real tomato cultivation scenes and is robust to issues such as fruit occlusion and variable lighting conditions is highly desired. In this study, we build a tomato detection model to automatically detect intact green tomatoes regardless of occlusions or fruit growth stage using deep learning approaches. The tomato detection model used faster region-based convolutional neural network (R-CNN) with Resnet-101 and transfer learned from the Common Objects in Context (COCO) dataset. The detection on test dataset achieved high average precision of 87.83% (intersection over union ? 0.5) and showed a high accuracy of tomato counting (R2 = 0.87). In addition, all the detected boxes were merged into one image to compile the tomato location map and estimate their size along one row in the greenhouse. By tomato detection, counting, location and size estimation, this method shows great potential for ripeness and yield prediction.
| S-EPMC7288109 | biostudies-literature
Project description:Understanding spin textures in magnetic systems is extremely important to the spintronics and it is vital to extrapolate the magnetic Hamiltonian parameters through the experimentally determined spin. It can provide a better complementary link between theories and experimental results. We demonstrate deep learning can quantify the magnetic Hamiltonian from magnetic domain images. To train the deep neural network, we generated domain configurations with Monte Carlo method. The errors from the estimations was analyzed with statistical methods and confirmed the network was successfully trained to relate the Hamiltonian parameters with magnetic structure characteristics. The network was applied to estimate experimentally observed domain images. The results are consistent with the reported results, which verifies the effectiveness of our methods. On the basis of our study, we anticipate that the deep learning techniques make a bridge to connect the experimental and theoretical approaches not only in magnetism but also throughout any scientific research.
| S-EPMC7518863 | biostudies-literature
Project description:The increasing rates of neurodevelopmental disorders (NDs) are threatening pregnant women, parents, and clinicians caring for healthy infants and children. NDs can initially start through embryonic development due to several reasons. Up to three in 1000 pregnant women have embryos with brain defects; hence, the primitive detection of embryonic neurodevelopmental disorders (ENDs) is necessary. Related work done for embryonic ND classification is very limited and is based on conventional machine learning (ML) methods for feature extraction and classification processes. Feature extraction of these methods is handcrafted and has several drawbacks. Deep learning methods have the ability to deduce an optimum demonstration from the raw images without image enhancement, segmentation, and feature extraction processes, leading to an effective classification process. This article proposes a new framework based on deep learning methods for the detection of END. To the best of our knowledge, this is the first study that uses deep learning techniques for detecting END. The framework consists of four stages which are transfer learning, deep feature extraction, feature reduction, and classification. The framework depends on feature fusion. The results showed that the proposed framework was capable of identifying END from embryonic MRI images of various gestational ages. To verify the efficiency of the proposed framework, the results were compared with related work that used embryonic images. The performance of the proposed framework was competitive. This means that the proposed framework can be successively used for detecting END.
| S-EPMC7169467 | biostudies-literature
Project description:Intense sun exposure is a major risk factor for the development of melanoma, an abnormal proliferation of skin cells. Yet, this more prevalent type of skin cancer can also develop in less-exposed areas, such as those that are shaded. Melanoma is the sixth most common type of skin cancer. In recent years, computer-based methods for imaging and analyzing biological systems have made considerable strides. This work investigates the use of advanced machine learning methods, specifically ensemble models with Auto Correlogram Methods, Binary Pyramid Pattern Filter, and Color Layout Filter, to enhance the detection accuracy of Melanoma skin cancer. These results suggest that the Color Layout Filter model of the Attribute Selection Classifier provides the best overall performance. Statistics for ROC, PRC, Kappa, F-Measure, and Matthews Correlation Coefficient were as follows: 90.96% accuracy, 0.91 precision, 0.91 recall, 0.95 ROC, 0.87 PRC, 0.87 Kappa, 0.91 F-Measure, and 0.82 Matthews Correlation Coefficient. In addition, its margins of error are the smallest. The research found that the Attribute Selection Classifier performed well when used in conjunction with the Color Layout Filter to improve image quality.
| S-EPMC10699043 | biostudies-literature
Project description:In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These methods include Asymmetry, Border, Color and Diameter (ABCD) method, seven-point detection method, Menzies method, and pattern analysis. They are used regularly by doctors for cancer diagnosis, although they are not considered very efficient for obtaining better performance. Moreover, considering all types of audience, the basic evaluation criteria are also discussed. The criteria include the receiver operating characteristic curve (ROC curve), Area under the ROC curve (AUC), F1 score, accuracy, specificity, sensitivity, precision, dice-coefficient, average accuracy, and Jaccard index. Previously used methods are considered inefficient, asking for better and smarter methods for cancer diagnosis. Artificial intelligence and cancer diagnosis are gaining attention as a way to define better diagnostic tools. In particular, deep neural networks can be successfully used for intelligent image analysis. The basic framework of how this machine learning works on medical imaging is provided in this study, i.e., pre-processing, image segmentation and post-processing. The second part of this manuscript describes the different deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial models (GANs), deep autoencoders (DANs), restricted Boltzmann's machine (RBM), stacked autoencoders (SAE), convolutional autoencoders (CAE), recurrent neural networks (RNNs), long short-term memory (LTSM), multi-scale convolutional neural network (M-CNN), multi-instance learning convolutional neural network (MIL-CNN). For each technique, we provide Python codes, to allow interested readers to experiment with the cited algorithms on their own diagnostic problems. The third part of this manuscript compiles the successfully applied deep learning models for different types of cancers. Considering the length of the manuscript, we restrict ourselves to the discussion of breast cancer, lung cancer, brain cancer, and skin cancer. The purpose of this bibliographic review is to provide researchers opting to work in implementing deep learning and artificial neural networks for cancer diagnosis a knowledge from scratch of the state-of-the-art achievements.
| S-EPMC6770116 | biostudies-literature
Project description:Simple Summary According to skin disease reports by healthcare organizations, the number of cases of skin disease is growing gradually over the years globally. In skin disease diagnosis, dermatologists examine skin cells by using a dermatoscope. Due to the global shortage of expert dermatologists, mainly in developing countries, an accurate early skin disease diagnosis is not possible. To automate the examination of skin disease images, computer-aided diagnosis-based tools are used in healthcare and medical environments. Computer-aided diagnosis employs machine learning including deep learning models on skin disease images to detect and classify skin diseases. The present work proposes a deep learning-based model to accurately detect skin diseases and classify them into a family of skin diseases using skin disease images. The proposed system demonstrated a performance improvement of 4% accuracy for skin disease detection and 9% accuracy for skin disease classification compared to the existing deep learning-based models. The proposed computer-aided tool can be used as an early skin diagnosis tool to assist dermatologists in healthcare and medical environments. Abstract Deep learning-based models have been employed for the detection and classification of skin diseases through medical imaging. However, deep learning-based models are not effective for rare skin disease detection and classification. This is mainly due to the reason that rare skin disease has very a smaller number of data samples. Thus, the dataset will be highly imbalanced, and due to the bias in learning, most of the models give better performances. The deep learning models are not effective in detecting the affected tiny portions of skin disease in the overall regions of the image. This paper presents an attention-cost-sensitive deep learning-based feature fusion ensemble meta-classifier approach for skin cancer detection and classification. Cost weights are included in the deep learning models to handle the data imbalance during training. To effectively learn the optimal features from the affected tiny portions of skin image samples, attention is integrated into the deep learning models. The features from the finetuned models are extracted and the dimensionality of the features was further reduced by using a kernel-based principal component (KPCA) analysis. The reduced features of the deep learning-based finetuned models are fused and passed into ensemble meta-classifiers for skin disease detection and classification. The ensemble meta-classifier is a two-stage model. The first stage performs the prediction of skin disease and the second stage performs the classification by considering the prediction of the first stage as features. Detailed analysis of the proposed approach is demonstrated for both skin disease detection and skin disease classification. The proposed approach demonstrated an accuracy of 99% on skin disease detection and 99% on skin disease classification. In all the experimental settings, the proposed approach outperformed the existing methods and demonstrated a performance improvement of 4% accuracy for skin disease detection and 9% accuracy for skin disease classification. The proposed approach can be used as a computer-aided diagnosis (CAD) tool for the early diagnosis of skin cancer detection and classification in healthcare and medical environments. The tool can accurately detect skin diseases and classify the skin disease into their skin disease family.
| S-EPMC9735681 | biostudies-literature
Project description:Recent studies have demonstrated the usefulness of convolutional neural networks (CNNs) to classify images of melanoma, with accuracies comparable to those achieved by dermatologists. However, the performance of a CNN trained with only clinical images of a pigmented skin lesion in a clinical image classification task, in competition with dermatologists, has not been reported to date. In this study, we extracted 5846 clinical images of pigmented skin lesions from 3551 patients. Pigmented skin lesions included malignant tumors (malignant melanoma and basal cell carcinoma) and benign tumors (nevus, seborrhoeic keratosis, senile lentigo, and hematoma/hemangioma). We created the test dataset by randomly selecting 666 patients out of them and picking one image per patient, and created the training dataset by giving bounding-box annotations to the rest of the images (4732 images, 2885 patients). Subsequently, we trained a faster, region-based CNN (FRCNN) with the training dataset and checked the performance of the model on the test dataset. In addition, ten board-certified dermatologists (BCDs) and ten dermatologic trainees (TRNs) took the same tests, and we compared their diagnostic accuracy with FRCNN. For six-class classification, the accuracy of FRCNN was 86.2%, and that of the BCDs and TRNs was 79.5% (p = 0.0081) and 75.1% (p < 0.00001), respectively. For two-class classification (benign or malignant), the accuracy, sensitivity, and specificity were 91.5%, 83.3%, and 94.5% by FRCNN; 86.6%, 86.3%, and 86.6% by BCD; and 85.3%, 83.5%, and 85.9% by TRN, respectively. False positive rates and positive predictive values were 5.5% and 84.7% by FRCNN, 13.4% and 70.5% by BCD, and 14.1% and 68.5% by TRN, respectively. We compared the classification performance of FRCNN with 20 dermatologists. As a result, the classification accuracy of FRCNN was better than that of the dermatologists. In the future, we plan to implement this system in society and have it used by the general public, in order to improve the prognosis of skin cancer.
| S-EPMC7465007 | biostudies-literature