Ontology highlight
ABSTRACT:
SUBMITTER: Xu L
PROVIDER: S-EPMC8161800 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Xu Luyan L Tong Jiahui J Wu Yiran Y Zhao Suwen S Lin Bo-Lin BL
Biophysical chemistry 20210528
In the new millennium, the outbreak of new coronavirus has happened three times: SARS-CoV, MERS-CoV, and SARS-CoV-2. Unfortunately, we still have no pharmaceutical weapons against the diseases caused by these viruses. The pandemic of SARS-CoV-2 reminds us the urgency to search new drugs with totally different mechanism that may target the weaknesses specific to coronaviruses. Herein, we disclose a computational evaluation of targeted oxidation strategy (TOS) for potential inhibition of SARS-CoV- ...[more]