RNA-Seq analysis of blood meal induced gene-expression changes in Aedes aegypti ovaries.

ABSTRACT:

Background

Transmission of pathogens by vector mosquitoes is intrinsically linked with mosquito's reproductive strategy because anautogenous mosquitoes require vertebrate blood to develop a batch of eggs. Each cycle of egg maturation is tightly linked with the intake of a fresh blood meal for most species. Mosquitoes that acquire pathogens during the first blood feeding can transmit the pathogens to susceptible hosts during subsequent blood feeding and also vertically to the next generation via infected eggs. Large-scale gene-expression changes occur following each blood meal in various tissues, including ovaries. Here we analyzed mosquito ovary transcriptome following a blood meal at three different time points to investigate blood-meal induced changes in gene expression in mosqui

SUBMITTER: Nag DK 

PROVIDER: S-EPMC8161926 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature