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DNA-polymer conjugates via the graft-through polymerisation of native DNA in water.


ABSTRACT: The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protection of the DNA bases.

SUBMITTER: Arkinstall LA 

PROVIDER: S-EPMC8168459 | biostudies-literature |

REPOSITORIES: biostudies-literature

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