Bone health in spacefaring rodents and primates: systematic review and meta-analysis.
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ABSTRACT:
SUBMITTER: Fu J
PROVIDER: S-EPMC8169759 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
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Bone health in spacefaring rodents and primates: systematic review and meta-analysis.
Fu Jingyan J Goldsmith Matthew M Crooks Sequoia D SD Condon Sean F SF Morris Martin M Komarova Svetlana V SV
NPJ microgravity 20210601 1
Animals in space exploration studies serve both as a model for human physiology and as a means to understand the physiological effects of microgravity. To quantify the microgravity-induced changes to bone health in animals, we systematically searched Medline, Embase, Web of Science, BIOSIS, and NASA Technical reports. We selected 40 papers focusing on the bone health of 95 rats, 61 mice, and 9 rhesus monkeys from 22 space missions. The percentage difference from ground control in rodents was -24 ...[more]
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