Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses.

ABSTRACT: Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.

SUBMITTER: Kim SJ 

PROVIDER: S-EPMC8170210 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature