Clinical and inflammatory characteristics of patients with asthma in the Spanish MEGA project cohort.

ABSTRACT:

Introduction

The MEGA (MEchanism underlying the Genesis and evolution of Asthma) project is a multicenter cohort study carried out in eight Spanish hospitals, gathering clinical, physiological, and molecular data from patients with asthma and multimorbidities in order to gain insight into the different physiopathological mechanisms involved in this disorder.

Material and methods

We report the baseline clinical and physiological characteristics and biomarker measures of adult participants in the project with the aim of better understanding the natural history and underlying mechanisms of asthma as well as the associated multimorbidities across different levels of severity. We carried out a detailed clinical examination, pulmonary function testing, measurement of fractional ex

SUBMITTER: Rial MJ 

PROVIDER: S-EPMC8173588 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature