Ontology highlight
ABSTRACT:
SUBMITTER: Wu CY
PROVIDER: S-EPMC8174449 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Wu Celeste Yin-Chieh CY Couto E Silva Alexandre A Citadin Cristiane T CT Clemons Garrett A GA Acosta Christina H CH Knox Brianne A BA Grames Mychal S MS Rodgers Krista M KM Lee Reggie Hui-Chao RH Lin Hung Wen HW
Prostaglandins, leukotrienes, and essential fatty acids 20201217
We previously discovered that palmitic acid methyl ester (PAME) is a potent vasodilator released from the sympathetic ganglion with vasoactive properties. Post-treatment with PAME can enhance cortical cerebral blood flow and functional learning and memory, while inhibiting neuronal cell death in the CA1 region of the hippocampus under pathological conditions (i.e. cerebral ischemia). Since mechanisms underlying PAME-mediated neuroprotection remain unclear, we investigated the possible neuroprote ...[more]