Insular Connectivity Is Associated With Self-Appraisal of Cognitive Function After a Concussion.

ABSTRACT: Concussion is associated with acute cognitive impairments, with declines in processing speed and reaction time being common. In the clinical setting, these issues are identified via symptom assessments and neurocognitive test (NCT) batteries. Practice guidelines recommend integrating both symptoms and NCTs into clinical decision-making, but correlations between these measures are often poor. This suggests that many patients experience difficulties in the self-appraisal of cognitive issues. It is presently unclear what neural mechanisms give rise to appraisal mismatch after a concussion. One promising target is the insula, which regulates aspects of cognition, particularly interoception and self-monitoring. The present study tested the hypothesis that appraisal mismatch is due to alt

SUBMITTER: Churchill NW 

PROVIDER: S-EPMC8175663 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature