Ontology highlight
ABSTRACT:
SUBMITTER: Siao AC
PROVIDER: S-EPMC8176213 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Siao An-Ci AC Shih Li-Jane LJ Lin Yen-Yue YY Tsuei Yi-Wei YW Kuo Yow-Chii YC Ku Hui-Chen HC Chuu Chih-Ping CP Hsiao Po-Jen PJ Kao Yung-Hsi YH
Frontiers in endocrinology 20210521
Endothelins induce many biological responses, and they are composed of three peptides: ET-1, ET-2, and ET-3. Reports have indicated that ET-1 regulates cell proliferation, adipogenesis, and other cell responses and that ET-3 stimulates the growth of gastrointestinal epithelial cells and melanocytes. However, the signalling pathways of ET3 that mediate the growth of fat cells are still unclear. Using 3T3-L1 white preadipocytes, we found that ET-3 induced increases in both cell number and BrdU inc ...[more]