Chronotherapy for morning blood pressure surge in hypertensive patients: a systematic review and meta-analysis.

ABSTRACT:

Background

The morning blood pressure surge (MBPS) is related to an exaggerated risk of cardiovascular diseases and mortality. With increasing attention on circadian change in blood pressure and extensive use of ambulatory blood pressure monitoring (ABPM), chronotherapy that administration of medication according to biological rhythm, is reported to improve cardiovascular outcomes. The aim of this study is to evaluate the influence of chronotherapy of antihypertensive drugs upon MBPS in hypertensive patients.

Methods

A search strategy was applied in Ovid MEDLINE, EMBASE, Cochrane (Wiley) CENTRAL Register of Controlled Trials, Cochrane Database of Systematic Reviews, and the Chinese Biomedical literature database. No language and date restrictions. Randomized controlled trial

SUBMITTER: Xie Z 

PROVIDER: S-EPMC8176711 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature