Transcriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni).

ABSTRACT:

Background

Copper was used for many years in aquaculture operations as an effective algaecide or a parasite treatment of fish. It is an essential nutrient with numerous functions in organisms, but is toxic at high concentrations. However, the toxicity of copper to fish remains unclear. In this study, we used the piebald naked carp, Gymnocypris eckloni, as a model. RNA-seq data from different tissues, including gills, kidney, and liver, were used to investigate the underlying mechanism of copper toxicology in G. eckloni.

Results

We compared the transcriptomes from different tissues with different time durations of copper ion treatment. After 72 h copper ion treatment, the number of genes with different expression in gills and liver changed dramatically, but not in kidneys. In

SUBMITTER: Jin W 

PROVIDER: S-EPMC8178853 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature