Spatial variation in the joint effect of extreme heat events and ozone on respiratory hospitalizations in California.

ABSTRACT: Extreme heat and ozone are co-occurring exposures that independently and synergistically increase the risk of respiratory disease. To our knowledge, no joint warning systems consider both risks; understanding their interactive effect can warrant use of comprehensive warning systems to reduce their burden. We examined heterogeneity in joint effects (on the additive scale) between heat and ozone at small geographical scales. A within-community matched design with a Bayesian hierarchical model was applied to study this association at the zip code level. Spatially varying relative risks due to interaction (RERI) were quantified to consider joint effects. Determinants of the spatial variability of effects were assessed using a random effects metaregression to consider the role of demographic/ne

SUBMITTER: Schwarz L 

PROVIDER: S-EPMC8179213 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature