Challenge of prostate MRI segmentation on T2-weighted images: inter-observer variability and impact of prostate morphology.

ABSTRACT:

Background

Accurate prostate zonal segmentation on magnetic resonance images (MRI) is a critical prerequisite for automated prostate cancer detection. We aimed to assess the variability of manual prostate zonal segmentation by radiologists on T2-weighted (T2W) images, and to study factors that may influence it.

Methods

Seven radiologists of varying levels of experience segmented the whole prostate gland (WG) and the transition zone (TZ) on 40 axial T2W prostate MRI images (3D T2W images for all patients, and both 3D and 2D images for a subgroup of 12 patients). Segmentation variabilities were evaluated based on: anatomical and morphological variation of the prostate (volume, retro-urethral lobe, intensity contrast between zones, presence of a PI-RADS ≥ 3 lesion), variation i

SUBMITTER: Montagne S 

PROVIDER: S-EPMC8179870 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature