Impact of a defunctioning ileostomy and time to stoma closure on bowel function after low anterior resection for rectal cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Impaired bowel function after low anterior resection (LAR) for rectal cancer is a frequent problem with a major impact on quality of life. The aim of this study was to assess the impact of a defunctioning ileostomy, and time to ileostomy closure on bowel function after LAR for rectal cancer.

Methods

We performed a systematic review based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement. Comprehensive literature searches were conducted using PubMed, Embase and Cochrane databases for articles published from 1989 up to August 2019. Analysis was performed using Review Manager (version 5.3) using a random-effects model.

Results

The search yielded 11 studies (1400 patients) that reported on functional outcome after LAR

SUBMITTER: Vogel I 

PROVIDER: S-EPMC8187190 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature