High Serum Anti-Mullerian Hormone Concentrations Are Associated With Poor Pregnancy Outcome in Fresh IVF/ICSI Cycle but Not Cumulative Live Birth Rate in PCOS Patients.

ABSTRACT:

Objective

To investigate the association between baseline serum Anti-Müllerian hormone (AMH) levels and IVF/ICSI outcomes in women with polycystic ovary syndrome (PCOS).

Design

Retrospective study.

Setting

Reproductive medicine center in a hospital.

Population

2436 PCOS patients (Rotterdam criteria) who underwent their first fresh IVF/ICSI cycles were divided into three groups on the basis of the <25th (Group 1, n=611), 25 to 75th (Group 2, n=1216), or >75th (Group 3, n=609) percentile of baseline serum AMH level.

Interventions

Baseline serum AMH levels measured on the 2-3 days of spontaneous menstrual cycle before IVF/ICSI treatment.

Main outcome measures

Live birth rate (LBR), cumulative live birth rate (CLBR), clinical pregnancy rate (CPR), and

SUBMITTER: Guo Y 

PROVIDER: S-EPMC8187895 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature