Catching viral breast cancer.

ABSTRACT: We have considered viruses and their contribution to breast cancer.

Mouse mammary tumour virus

The prevalence of mouse mammary tumour virus (MMTV) is 15-fold higher in human breast cancer than in normal and benign human breast tissue controls. Saliva is the most plausible means of transmission. MMTV has been identified in dogs, cats, monkeys, mice and rats. The causal mechanisms include insertional oncogenesis and mutations in the protective enzyme ABOBEC3B.

Human papilloma virus

The prevalence of high risk human papilloma viruses (HPV) is frequently six fold higher in breast cancer than in normal and benign breast tissue controls. Women who develop HPV associated cervical cancer are at higher than normal risk of developing HPV associated breast cancer. Koilocytes have been i

SUBMITTER: Lawson JS 

PROVIDER: S-EPMC8191131 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature