Ontology highlight
ABSTRACT:
SUBMITTER: Devos T
PROVIDER: S-EPMC8195783 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Devos Timothy T Havelange Violaine V Theunissen Koen K Meers Stef S Benghiat Fleur Samantha FS Gadisseur Alain A Vanstraelen Gaëtan G Vellemans Hélène H Bailly Benjamin B Granacher Nikki N Lewalle Philippe P De Becker Ann A Van Eygen Koen K Janssen Mia M Triffet Agnes A Vrelust Inge I Deeren Dries D Mazure Dominiek D Bekaert Julie J Beck Michael M Selleslag Dominik D
Annals of hematology 20210504 7
Data on clinical use of ponatinib are limited. This prospective registry aimed to evaluate outcomes of ponatinib treatment in routine practice over 3 years (2016-2019) in Belgium (NCT03678454). Patients with chronic myeloid leukemia (CML) or Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) were treated with ponatinib per current label. Fifty patients (33 CML and 17 Ph+ ALL) were enrolled. Fifty-five percent of CML and 29% of Ph+ ALL patients had received ≥3 prior tyrosin ...[more]