The association between prenatal concentrations of polybrominated diphenyl ether and child cognitive and psychomotor function.

ABSTRACT: Previous studies suggest a negative association between prenatal polybrominated diphenyl ethers (PBDEs) exposure and child cognitive and psychomotor development. However, the timing of the relationship between PBDE exposure and neurodevelopment is still unclear. We examined the association between PBDE concentration at two different prenatal times (early and late pregnancy) and cognitive function in children 6-8 years of age.

Methods

Eight hundred pregnant women were recruited between 2007 and 2009 from Sherbrooke, Canada. Four PBDE congeners (BDE-47, -99, -100, and -153) were measured in maternal plasma samples collected during early pregnancy (12 weeks of gestation) and at delivery. At 6-8 years of age, 355 children completed a series of subtests spanning multiple neuropsychologic

SUBMITTER: Solazzo G 

PROVIDER: S-EPMC8196085 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature