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Ablation in Pancreatic Cancer: Past, Present and Future.


ABSTRACT: The insidious onset and aggressive nature of pancreatic cancer contributes to the poor treatment response and high mortality of this devastating disease. While surgery, chemotherapy and radiation have contributed to improvements in overall survival, roughly 90% of those afflicted by this disease will die within 5 years of diagnosis. The developed ablative locoregional treatment modalities have demonstrated promise in terms of overall survival and quality of life. In this review, we discuss some of the recent studies demonstrating the safety and efficacy of ablative treatments in patients with locally advanced pancreatic cancer.

SUBMITTER: Narayanan G 

PROVIDER: S-EPMC8196600 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Ablation in Pancreatic Cancer: Past, Present and Future.

Narayanan Govindarajan G   Daye Dania D   Wilson Nicole M NM   Noman Raihan R   Mahendra Ashwin M AM   Doshi Mehul H MH  

Cancers 20210521 11


The insidious onset and aggressive nature of pancreatic cancer contributes to the poor treatment response and high mortality of this devastating disease. While surgery, chemotherapy and radiation have contributed to improvements in overall survival, roughly 90% of those afflicted by this disease will die within 5 years of diagnosis. The developed ablative locoregional treatment modalities have demonstrated promise in terms of overall survival and quality of life. In this review, we discuss some  ...[more]

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