Hippocampal subfield volumes are associated with verbal memory after first-ever ischemic stroke.

ABSTRACT:

Introduction

Hippocampal subfield volumes are more closely associated with cognitive impairment than whole hippocampal volume in many diseases. Both memory and whole hippocampal volume decline after stroke. Understanding the subfields' temporal evolution could reveal valuable information about post-stroke memory.

Methods

We sampled 120 participants (38 control, 82 stroke), with cognitive testing and 3T-MRI available at 3 months and 3 years, from the Cognition and Neocortical Volume after Stroke (CANVAS) study. Verbal memory was assessed using the Hopkins Verbal Learning Test-Revised. Subfields were delineated using FreeSurfer. We used partial Pearson's correlation to assess the associations between subfield volumes and verbal memory scores, adjusting for years of education,

SUBMITTER: Khlif MS 

PROVIDER: S-EPMC8197170 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature