Ontology highlight
ABSTRACT:
SUBMITTER: Kawano R
PROVIDER: S-EPMC8197374 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Kawano Rena R Okamura Takuro T Hashimoto Yoshitaka Y Majima Saori S Senmaru Takafumi T Ushigome Emi E Asano Mai M Yamazaki Masahiro M Takakuwa Hiroshi H Sasano Ryoichi R Nakanishi Naoko N Hamaguchi Masahide M Fukui Michiaki M
International journal of molecular sciences 20210524 11
<h4>Background</h4>Erythritol, a sugar alcohol, is widely used as a substitute for sugar in diets for patients with diabetes or obesity.<h4>Methods</h4>In this study, we aimed to investigate the effects of erythritol on metabolic disorders induced by a high-fat diet in C57BL/6J mice, while focusing on changes in innate immunity.<h4>Results</h4>Mice that were fed a high-fat diet and administered water containing 5% erythritol (Ery group) had markedly lower body weight, improved glucose tolerance, ...[more]