Dataset Information

Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study.

ABSTRACT: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level ≥ 8 g/dL. During the study period, 529 patients received RBC transfusion. The median age was 74 (59-85) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0-7.8) g/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (≥8 g/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29-3.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53-3.94), and older age (OR: 1.02/year; 95% CI: 1.01-1.04). RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold.

SUBMITTER: Peyrony O

PROVIDER: S-EPMC8199757 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study.

Peyrony Olivier O Gamelon Danaé D Brune Romain R Chauvin Anthony A Ghazali Daniel Aiham DA Yordanov Youri Y Arsicaud Aude A Gilleron Pauline P Curac Sonja S Richard Marie-Caroline MC Feral-Pierssens Anne-Laure AL Villoing Barbara B Beaune Sébastien S Goulet Hélène H Fontaine Jean-Paul JP François Anne A Pirenne France F

Journal of clinical medicine 20210602 11

<h4>Background</h4>We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting.<h4>Methods</h4>This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion H ...[more]

PMID: 34199655

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Dataset Information

Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study.

Publications

Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study.

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