Dataset Information
Levonorgestrel-releasing intrauterine system for endometrial hyperplasia.
Ontology highlight
ABSTRACT:
SUBMITTER: Mittermeier T
PROVIDER: S-EPMC8200645 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Levonorgestrel-releasing intrauterine system for endometrial hyperplasia.
The Cochrane database of systematic reviews 20200906
<h4>Background</h4>In the absence of treatment, endometrial hyperplasia (EH) can progress to endometrial cancer, particularly in the presence of histologic nuclear atypia. The development of EH results from exposure of the endometrium to oestrogen unopposed by progesterone. Oral progestogens have been used as treatment for EH without atypia, and in some cases of EH with atypia in women who wish to preserve fertility or who cannot tolerate surgery. EH without atypia is associated with a low risk ...[more]