Ontology highlight
ABSTRACT:
SUBMITTER: Lewin TD
PROVIDER: S-EPMC8208926 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Lewin Thomas D TD Royall Amy H AH Holland Peter W H PWH
Journal of molecular evolution 20210607 6
The majority of homeobox genes are highly conserved across animals, but the eutherian-specific ETCHbox genes, embryonically expressed and highly divergent duplicates of CRX, are a notable exception. Here we compare the ETCHbox genes of 34 mammalian species, uncovering dynamic patterns of gene loss and tandem duplication, including the presence of a large tandem array of LEUTX loci in the genome of the European rabbit (Oryctolagus cuniculus). Despite extensive gene gain and loss, all sampled spec ...[more]