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Convolutional neural network for diagnosis of viral pneumonia and COVID-19 alike diseases.

ABSTRACT: Reverse-Transcription Polymerase Chain Reaction (RT-PCR) method is currently the gold standard method for detection of viral strains in human samples, but this technique is very expensive, take time and often leads to misdiagnosis. The recent outbreak of COVID-19 has led scientists to explore other options such as the use of artificial intelligence driven tools as an alternative or a confirmatory approach for detection of viral pneumonia. In this paper, we utilized a Convolutional Neural Network (CNN) approach to detect viral pneumonia in x-ray images using a pretrained AlexNet model thereby adopting a transfer learning approach. The dataset used for the study was obtained in the form of optical Coherence Tomography and chest X-ray images made available by Kermany et al. (2018, https://doi.org/10.17632/rscbjbr9sj.3) with a total number of 5853 pneumonia (positive) and normal (negative) images. To evaluate the average efficiency of the model, the dataset was split into on 50:50, 60:40, 70:30, 80:20 and 90:10 for training and testing respectively. To evaluate the performance of the model, 10 K Cross-validation was carried out. The performance of the model using overall dataset was compared with the means of cross-validation and the currents state of arts. The classification model has shown high performance in terms of accuracy, sensitivity and specificity. 70:30 split performed better compare to other splits with accuracy of 98.73%, sensitivity of 98.59% and specificity of 99.84%.

SUBMITTER: Umar Ibrahim A

PROVIDER: S-EPMC8209916 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:Background and objectiveSARS-CoV-2, a novel strain of coronavirus' also called coronavirus disease 19 (COVID-19), a highly contagious pathogenic respiratory viral infection emerged in December 2019 in Wuhan, a city in China's Hubei province without an obvious cause. Very rapidly it spread across the globe (over 200 countries and territories) and finally on 11 March 2020 World Health Organisation characterized it as a "pandemic". Although it has low mortality of around 3% as of 18 May 2021 it has already infected 164,316,270 humans with 3,406,027 unfortunate deaths. Undoubtedly the world was rocked by the COVID-19 pandemic, but researchers rose to all manner of challenges to tackle this pandemic by adopting the shreds of evidence of ML and AI in previous epidemics to develop novel models, methods, and strategies. We aim to provide a deeper insight into the convolutional neural network which is the most notable and extensively adopted technique on radiographic visual imagery to help expert medical practitioners and researchers to design and finetune their state-of-the-art models for their applicability in the arena of COVID-19.MethodIn this study, a deep convolutional neural network, its layers, activation and loss functions, regularization techniques, tools, methods, variants, and recent developments were explored to find its applications for COVID-19 prognosis. The pipeline of a general architecture for COVID-19 prognosis has also been proposed.ResultThis paper highlights recent studies of deep CNN and its applications for better prognosis, detection, classification, and screening of COVID-19 to help researchers and expert medical community in multiple directions. It also addresses a few challenges, limitations, and outlooks while using such methods for COVID-19 prognosis.ConclusionThe recent and ongoing developments in AI, MI, and deep learning (Deep CNN) has shown promising results and significantly improved performance metrics for screening, prediction, detection, classification, forecasting, medication, treatment, contact tracing, etc. to curtail the manual intervention in medical practice. However, the research community of medical experts is yet to recognize and label the benchmark of the deep learning framework for effective detection of COVID-19 positive cases from radiology imagery.

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Convolutional neural network for diagnosis of viral pneumonia and COVID-19 alike diseases.

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