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ABSTRACT: Objectives
To evaluate the concordance between Google Maps® application (GM®) and clinical practice measurements of ambulatory function (e.g., Ambulation Score (AS) and respective Expanded Disability Status Scale (EDSS)) in people with multiple sclerosis (pwMS).Materials and methods
This is a cross-sectional multicenter study. AS and EDSS were calculated using GM® and routine clinical methods; the correspondence between the two methods was assessed. A multinomial logistic model is investigated which demographic (age, sex) and clinical features (e.g., disease subtype, fatigue, depression) might have influenced discrepancies between the two methods.Results
Two hundred forty-three pwMS were included; discrepancies in AS and in EDDS assessments between GM® and routine clinical methods were found in 81/243 (33.3%) and 74/243 (30.4%) pwMS, respectively. Progressive phenotype (odds ratio [OR] = 2.8; 95% confidence interval [CI] 1.1-7.11, p = 0.03), worse fatigue (OR = 1.03; 95% CI 1.01-1.06, p = 0.01), and more severe depression (OR = 1.1; 95% CI 1.04-1.17, p = 0.002) were associated with discrepancies between GM® and routine clinical scoring.Conclusion
GM® could easily be used in a real-life clinical setting to calculate the AS and the related EDSS scores. GM® should be considered for validation in further clinical studies.
SUBMITTER: Lavorgna L
PROVIDER: S-EPMC8211455 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Lavorgna Luigi L Iaffaldano Pietro P Abbadessa Gianmarco G Lanzillo Roberta R Esposito Sabrina S Ippolito Domenico D Sparaco Maddalena M Cepparulo Simone S Lus Giacomo G Viterbo Rosa R Clerico Marinella M Trojsi Francesca F Ragonese Paolo P Borriello Giovanna G Signoriello Elisabetta E Palladino Raffaele R Moccia Marcello M Brigo Francesco F Troiano Maria M Tedeschi Gioacchino G Bonavita Simona S
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20210617 2
<h4>Objectives</h4>To evaluate the concordance between Google Maps® application (GM®) and clinical practice measurements of ambulatory function (e.g., Ambulation Score (AS) and respective Expanded Disability Status Scale (EDSS)) in people with multiple sclerosis (pwMS).<h4>Materials and methods</h4>This is a cross-sectional multicenter study. AS and EDSS were calculated using GM® and routine clinical methods; the correspondence between the two methods was assessed. A multinomial logistic model i ...[more]