Unknown

Dataset Information

0

TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis.


ABSTRACT: Differential concentrations of phytohormone trigger distinct outputs, which provides a mechanism for the plasticity of plant development and an adaptation strategy among plants to changing environments. However, the underlying mechanisms of the differential responses remain unclear. Here we report that a high concentration of auxin, distinct from the effect of low auxin concentration, enhances abscisic acid (ABA) responses in Arabidopsis thaliana, which partially relies on TRANS-MEMBERANE KINASE 1 (TMK1), a key regulator in auxin signaling. We show that high auxin and TMK1 play essential and positive roles in ABA signaling through regulating ABA INSENSITIVE 1 and 2 (ABI1/2), two negative regulators of the ABA pathway. TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses. This TMK1-dependent auxin signaling in the regulation of ABA responses provides a possible mechanism underlying the high auxin responses in plants and an alternative mechanism involved in the coordination between auxin and ABA signaling.

SUBMITTER: Yang J 

PROVIDER: S-EPMC8214701 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4084465 | biostudies-literature
| S-EPMC3777161 | biostudies-literature
| S-EPMC439007 | biostudies-other
| S-EPMC6779896 | biostudies-other
| S-EPMC1939880 | biostudies-literature
| S-EPMC4455775 | biostudies-literature
| S-EPMC6508792 | biostudies-literature
| S-EPMC9083366 | biostudies-literature
| S-EPMC3780901 | biostudies-other
| S-EPMC2664011 | biostudies-literature