Ontology highlight
ABSTRACT:
SUBMITTER: Eroglu B
PROVIDER: S-EPMC8219765 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Eroglu Binnur B Genova Evan E Zhang Quanguang Q Su Yun Y Shi Xingming X Isales Carlos C Eroglu Ali A
Scientific reports 20210622 1
The plasticity and proliferative capacity of stem cells decrease with aging, compromising their tissue regenerative potential and therapeutic applications. This decline is directly linked to mitochondrial dysfunction. Here, we present an effective strategy to reverse aging of mouse bone marrow mesenchymal stem cells (BM-MSCs) by restoring their mitochondrial functionality using photobiomodulation (PBM) therapy. Following the characterization of young and aged MSCs, our results show that a near-i ...[more]