Intramammary Immunisation Provides Short Term Protection Against Mannheimia haemolytica Mastitis in Sheep.

ABSTRACT: Mastitis affects both dairy and meat/wool sheep industries with losses due to reductions in milk quality and quantity, increased treatment costs and restricted lamb growth. Effective vaccines would be important tools for mastitis control. However, the development of vaccines against mastitis has proved challenging due to the failure to target protective immunity to the mammary gland. In order to target responses to the mammary gland, this study tested whether local administration directly into the gland through the teat canal or in the udder skin confers protection against an intramammary infection. In this study, we tested a vaccine that confers protection against respiratory disease caused by Mannheimia haemolytica to determine if it also protects against intramammary infection by

SUBMITTER: Tassi R 

PROVIDER: S-EPMC8222732 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature