Ontology highlight
ABSTRACT:
SUBMITTER: Megas IF
PROVIDER: S-EPMC8223971 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Megas Ioannis-Fivos IF Simons David D Kim Bong-Sung BS Stoppe Christian C Piatkowski Andrzej A Fikatas Panagiotis P Fuchs Paul Christian PC Bastiaanse Jacqueline J Pallua Norbert N Bernhagen Jürgen J Grieb Gerrit G
Healthcare (Basel, Switzerland) 20210521 6
(1) Background: Nowadays, the use of microsurgical free flaps is a standard operative procedure in reconstructive surgery. Still, thrombosis of the microanastomosis is one of the most fatal postoperative complications. Clinical evaluation, different technical devices and laboratory markers are used to monitor critical flap perfusion. Macrophage migration inhibitory factor (MIF), a structurally unique cytokine with chemokine-like characteristics, could play a role in predicting vascular problems ...[more]