SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2.
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ABSTRACT: During the COVID-19 pandemic, the development of sensitive and rapid techniques for detection of viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool for new techniques due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection are either inapplicable for quantitative determination or have sophisticated and expensive construction and implementation. In this paper, we provide a SERS-aptasensor based on colloidal solutions which combines rapidity and specificity in quantitative determination of SARS-CoV-2 virus, discriminating it from the other respiratory viruses.
SUBMITTER: Zavyalova E
PROVIDER: S-EPMC8228355 | biostudies-literature |
REPOSITORIES: biostudies-literature
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