Generation of Therapeutically Potent Spheroids from Human Endometrial Mesenchymal Stem/Stromal Cells.
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ABSTRACT:
SUBMITTER: Domnina A
PROVIDER: S-EPMC8229788 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
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Generation of Therapeutically Potent Spheroids from Human Endometrial Mesenchymal Stem/Stromal Cells.
Domnina Alisa A Alekseenko Larisa L Kozhukharova Irina I Lyublinskaya Olga O Shorokhova Mariia M Zenin Valeriy V Fridlyanskaya Irina I Nikolsky Nikolay N
Journal of personalized medicine 20210525 6
Endometrial mesenchymal stem/stromal cells (eMSCs) hold great promise in bioengineering and regenerative medicine due to their high expansion potential, unique immunosuppressive properties and multilineage differentiation capacity. Usually, eMSCs are maintained and applied as a monolayer culture. Recently, using animal models with endometrial and skin defects, we showed that formation of multicellular aggregates known as spheroids from eMSCs enhances their tissue repair capabilities. In this wor ...[more]
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