Lymphopenia Is Associated With Poor Outcomes of Patients With Community-Acquired Pneumonia and Sepsis.

ABSTRACT:

Background

Lymphopenia is a marker of poor prognosis in patients with community-acquired pneumonia (CAP), yet its impact on outcomes in patients with CAP and sepsis remains unknown. We aim to investigate the impact of lymphopenia on outcomes, risk of intensive care unit (ICU) admission, and mortality in CAP patients with sepsis.

Methods

This was a retrospective, observational study of prospectively collected data from an 800-bed tertiary teaching hospital (2005-2019).

Results

Of the 2203 patients with CAP and sepsis, 1347 (61%) did not have lymphopenia, while 856 (39%) did. When compared with the nonlymphopenic group, patients with sepsis and lymphopenia more frequently required ICU admission (P = .001), had a longer hospital length of stay (P ˂ .001), a

SUBMITTER: Cilloniz C 

PROVIDER: S-EPMC8231373 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature