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Butyryl-cholinesterase deficiency: A case report of delayed recovery after general anaesthesia.


ABSTRACT:

Background

Apnoea and prolonged paralysis after succinylcholine administration is not uncommon occurrence in anaesthetic practice. It occurs due to inherited or acquired deficiency of butyrylcholinesterase.

Case report

Here we report a case of succinylcholine apnoea for 2 h in a 5 years old girl who was anaesthetized for bronchoscopic extraction of a foreign body. She was subsequently kept on assisted ventilation. She recovered few minutes after I.V. atropine and naloxone. Laboratory investigation revealed low cholinesterase activity. Thus the girl was given 150 mL fresh frozen plasma. She has been discharged the next day after complete recovery.

Conclusion

As the genetic analysis was not available to confirm the diagnosis of atypical variant of cholinesterase. The fa

SUBMITTER: Al-Emam A 

PROVIDER: S-EPMC8233168 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature