Framing Effects on Decision-Making for Diagnostic Genetic Testing: Results from a Randomized Trial.

ABSTRACT: Genetic testing is increasingly part of routine clinical care. However, testing decisions may be characterized by regret as findings also implicate blood relatives. It is not known if genetic testing decisions are affected by the way information is presented (i.e., framing effects). We employed a randomized factorial design to examine framing effects on hypothetical genetic testing scenarios (common, life-threatening disease and rare, life-altering disease). Participants (n = 1012) received one of six decision frames: choice, default (n = 2; opt-in, opt-out), or enhanced choice (n = 3, based on the Theory of Planned Behavior). We compared testing decision, satisfaction, regret, and decision cognitions across decision frames and between scenarios. Participants randomize

SUBMITTER: Dwyer AA 

PROVIDER: S-EPMC8234313 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature