Serum metabolomics in chickens infected with Cryptosporidium baileyi.

ABSTRACT:

Background

Cryptosporidium baileyi is an economically important zoonotic pathogen that causes serious respiratory symptoms in chickens for which no effective control measures are currently available. An accumulating body of evidence indicates the potential and usefulness of metabolomics to further our understanding of the interaction between pathogens and hosts, and to search for new diagnostic or pharmacological biomarkers of complex microorganisms. The aim of this study was to identify the impact of C. baileyi infection on the serum metabolism of chickens and to assess several metabolites as potential diagnostic biomarkers for C. baileyi infection.

Methods

Ultraperformance liquid chromatography-mass spectrometry (UPLC-MS) and subsequent multivariate statistical analysis we

SUBMITTER: Wu XM 

PROVIDER: S-EPMC8235856 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature