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SARS-CoV-2 first contact: Spike-ACE2 interactions in COVID-19.

ABSTRACT: The full-length human ACE2 in complex with B⁰ AT1 is anchored to two S in open pre-fusion state which allows establishing pre-invasion interactions with the ACE2 N-terminal domain.

SUBMITTER: Nesci S

PROVIDER: S-EPMC8239675 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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SARS-CoV-2 first contact: Spike-ACE2 interactions in COVID-19.

Nesci Salvatore S

Chemical biology & drug design 20210621 2

The full-length human ACE2 in complex with B<sup>0</sup> AT1 is anchored to two S in open pre-fusion state which allows establishing pre-invasion interactions with the ACE2 N-terminal domain. ...[more]

PMID: 34047452

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