Changing Drivers of Mortality Among Patients Referred for Cardiac Stress Testing.

ABSTRACT:

Objective

To identify temporal shifts in coronary artery disease (CAD) risk factor profiles, clinical parameters, and corresponding mortality rates among patients referred for radionuclide stress testing over 22 years.

Patients and methods

We assessed 39,750 patients with suspected CAD ("diagnostic" patients) and 10,982 patients with known CAD who underwent radionuclide stress testing between January 2, 1991, and December 31, 2012, and were followed up for at least 5 years (median, 12.7 years).

Results

Among both diagnostic patients and those with known CAD, there was a marked temporal decline in typical angina and myocardial ischemia. However, several risk factors for disease progressively increased, including diabetes, obesity, and hypertension. In addition, the nee

SUBMITTER: Rozanski A 

PROVIDER: S-EPMC8240348 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature