Unknown

Dataset Information

0

Pangenomics reveals alternative environmental lifestyles among chlamydiae.


ABSTRACT: Chlamydiae are highly successful strictly intracellular bacteria associated with diverse eukaryotic hosts. Here we analyzed metagenome-assembled genomes of the "Genomes from Earth's Microbiomes" initiative from diverse environmental samples, which almost double the known phylogenetic diversity of the phylum and facilitate a highly resolved view at the chlamydial pangenome. Chlamydiae are defined by a relatively large core genome indicative of an intracellular lifestyle, and a highly dynamic accessory genome of environmental lineages. We observe chlamydial lineages that encode enzymes of the reductive tricarboxylic acid cycle and for light-driven ATP synthesis. We show a widespread potential for anaerobic energy generation through pyruvate fermentation or the arginine deiminase pathway, and we add lineages capable of molecular hydrogen production. Genome-informed analysis of environmental distribution revealed lineage-specific niches and a high abundance of chlamydiae in some habitats. Together, our data provide an extended perspective of the variability of chlamydial biology and the ecology of this phylum of intracellular microbes.

SUBMITTER: Kostlbacher S 

PROVIDER: S-EPMC8242063 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC2821981 | biostudies-literature
| S-EPMC4949044 | biostudies-literature
| S-EPMC7240083 | biostudies-literature
| S-EPMC6946804 | biostudies-literature
| S-EPMC8725406 | biostudies-literature
| S-EPMC4865325 | biostudies-literature
| S-EPMC7022738 | biostudies-literature
| S-EPMC3019940 | biostudies-literature
| S-EPMC3901455 | biostudies-literature
| S-EPMC7145651 | biostudies-literature