Ontology highlight
ABSTRACT:
SUBMITTER: Hiller M
PROVIDER: S-EPMC8242265 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Hiller Monika M Geissler Miriam M Janssen George G van Veelen Peter P Aartsma-Rus Annemieke A Spitali Pietro P
Genomics, proteomics & bioinformatics 20200801 4
Muscle formation is a coordinated process driven by extensive gene expression changes where single cells fuse together to form multinucleated muscle fibers. Newly synthesized mRNAs are then regulated by RNA binding proteins (RBPs), affecting post-transcriptional transcript metabolism. Here, we determined how large-scale gene expression changes affect the catalog of RBPs by studying proliferating and differentiated muscle cells in healthy and dystrophic conditions. Transcriptomic analysis showed ...[more]